Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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CX-6258
CAS:CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.Formula:C26H24ClN3O3Purity:95.88%Color and Shape:SolidMolecular weight:461.94Ref: TM-T1834
1mg37.00€5mg80.00€10mg106.00€25mg208.00€50mg311.00€100mg472.00€200mg658.00€1mL*10mM (DMSO)81.00€Anti-PARP1 Antibody (7A800)
Anti-PARP1 Antibody (7A800) is an antibody targeting PARP1. Anti-PARP1 Antibody (7A800) can be used in ELISA, WB, IHC.Color and Shape:Odour LiquidI-BET151
CAS:I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).Formula:C23H21N5O3Purity:97.34% - 99.63%Color and Shape:SolidMolecular weight:415.44Ref: TM-T2120
1mg48.00€2mg65.00€5mg96.00€10mg115.00€25mg202.00€50mg339.00€100mg507.00€500mg1,130.00€1mL*10mM (DMSO)105.00€Annaosanchun
CAS:Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).Formula:C19H32O3Purity:99.58%Color and Shape:SolidMolecular weight:308.46INCB-057643
CAS:INCB057643 is a potent, selective and orally bioavailable BET inhibitor.Formula:C20H21N3O5SPurity:99.50%Color and Shape:SolidMolecular weight:415.46Ref: TM-T5417
1mg42.00€5mg90.00€10mg140.00€25mg245.00€50mg368.00€100mg500.00€200mg688.00€1mL*10mM (DMSO)90.00€PBRM1-BD2-IN-5
CAS:PBRM1-BD2-IN-5 is a potent inhibitor of the PBRM1 Bromodomain, demonstrating dissociation constant (Kd) values of 1.5 μM and 3.9 μM for PBRM1-BD2 and PBRM1-BD5Formula:C15H13ClN2OPurity:99.55%Color and Shape:SoildMolecular weight:272.73Ref: TM-T60159
1mg96.00€2mg125.00€5mg188.00€10mg301.00€25mg454.00€50mg605.00€100mg837.00€500mg1,681.00€1mL*10mM (DMSO)180.00€Benzamide
CAS:Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.Formula:C7H7NOPurity:99.66%Color and Shape:Colorless Crystals Physical Description White Powder (Ntp 1992)Molecular weight:121.14Antiproliferative agent-25
Antiproliferative Agent-25 (Compound 3s4) is a selective PRMT5 inhibitor displaying an IC50 of 0.11 μM.Formula:C20H21BrN2O2Purity:98%Color and Shape:SolidMolecular weight:401.3BRD7-IN-2
BRD7-IN-2 (compound 2-77) is a potent selective inhibitor of bromodomain-containing protein 7 (BRD7), exhibiting significant anti-proliferative activity inFormula:C18H18N2O3Purity:98%Color and Shape:SolidMolecular weight:310.35Dot1L-IN-8
Dot1L-IN-8 (Compound 15) is an effective Dot1L inhibitor. It suppresses the viability of HL-60, K562, MV4-11, HH, and KG-1 cells, with IC50 values of 0.45, 1.03, 0.68, 1.66, and 1.12 μM, respectively.Formula:C41H53N7O3SColor and Shape:SolidMolecular weight:723.97RN-1 dihydrochloride
CAS:RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).Formula:C23H31Cl2N3O2Purity:99.61%Color and Shape:SolidMolecular weight:452.42MI-538
CAS:MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).Formula:C27H25F3N8OSPurity:100% - 99.31%Color and Shape:SolidMolecular weight:566.6Ref: TM-T16072
1mg64.00€5mg116.00€10mg188.00€25mg356.00€50mg535.00€100mg730.00€1mL*10mM (DMSO)145.00€MS049
CAS:MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.Formula:C15H24N2OPurity:≥95%Color and Shape:SolidMolecular weight:248.36Ref: TM-T4378
2mg35.00€5mg51.00€10mg85.00€25mg158.00€50mg235.00€100mg354.00€200mg520.00€1mL*10mM (DMSO)55.00€SIRT5 inhibitor 8
CAS:SIRT5 inhibitor 8 (compound 10) is a moderately selective and substrate-competitive SIRT5 inhibitor with IC50=5.38 μM, with potential anticancer effects.Formula:C22H25ClN8O2SPurity:99.68%Color and Shape:SolidMolecular weight:501Ilginatinib
CAS:Ilginatinib (NS-018) is a highly active and orally bioavailable inhibitor of JAK2.Formula:C21H20FN7Purity:98.40% - 99.01%Color and Shape:SolidMolecular weight:389.43Ref: TM-T12266
1mg64.00€5mg138.00€10mg187.00€25mg273.00€50mg393.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)133.00€MS417
CAS:MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weakFormula:C20H19ClN4O2SPurity:99.87%Color and Shape:SolidMolecular weight:414.91SR-0813
CAS:SR-0813 is a potent and selective inhibitor of the YEATS domain in ENL/AF9.Formula:C25H32N6O3SPurity:99.72%Color and Shape:SolidMolecular weight:496.62Ref: TM-T40229
1mg42.00€5mg90.00€10mg131.00€25mg266.00€50mg405.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)89.00€MC3343
CAS:MC3343, a DNMT1/3A inhibitor, affects tumor proliferation by blocking osteosarcoma cells in the G1 or G2/M phase and induces osteogenic differentiation.Formula:C27H23N7OPurity:99.73%Color and Shape:SolidMolecular weight:461.52Ref: TM-T203345
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€200mg2,555.00€DS79932728
CAS:DS79932728 is an orally active inhibitor of G9a and GLP, with IC50 values of 12.6 nM and 75.7 nM, respectively. It induces the production of γ-globin, thereby increasing fetal hemoglobin (HbF) levels. In cynomolgus monkey models, DS79932728 enhances the proportion of F-reticulocytes (F-rets) and shows good oral absorption characteristics.Formula:C19H25N3OColor and Shape:SolidMolecular weight:311.421BRM/BRG1 ATP Inhibitor-1
CAS:BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A memberFormula:C11H9F3N4O2SPurity:98.17% - 99.84%Color and Shape:SolidMolecular weight:318.27Ref: TM-T10616
1mg396.00€5mg612.00€10mg905.00€25mg1,320.00€50mg1,786.00€100mg2,442.00€1mL*10mM (DMSO)465.00€
