Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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BI 2536
CAS:BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.Formula:C28H39N7O3Purity:98% - 99.88%Color and Shape:SolidMolecular weight:521.65Ref: TM-T6173
1mg46.00€2mg59.00€5mg87.00€10mg103.00€25mg124.00€50mg197.00€100mg350.00€500mg840.00€1mL*10mM (DMSO)97.00€JBJ-04-125-02
CAS:JBJ-04-125-02: Oral EGFR inhibitor, targets EGFRL858R/T790M with 0.26 nM IC50, halts cancer growth, anti-tumor.Formula:C29H26FN5O3SPurity:98%Color and Shape:SolidMolecular weight:543.61(R)-CR8
CAS:(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.Formula:C24H29N7OPurity:98.41%Color and Shape:SolidMolecular weight:431.53Ref: TM-T12617L
1mg66.00€5mg144.00€10mg210.00€25mg356.00€50mg525.00€100mg747.00€1mL*10mM (DMSO)159.00€JANEX-1
CAS:JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formula:C16H15N3O3Purity:98% - 99.73%Color and Shape:SolidMolecular weight:297.31Ref: TM-T2045
1mg44.00€2mg55.00€5mg92.00€10mg150.00€25mg248.00€50mg444.00€100mg652.00€500mg1,378.00€1mL*10mM (DMSO)92.00€JAK3-IN-7
CAS:JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction afterFormula:C17H20N6OPurity:98.81%Color and Shape:SolidMolecular weight:324.384'-Methoxychalcone
CAS:4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.Formula:C16H14O2Purity:99.86%Color and Shape:SolidMolecular weight:238.28CPI-455
CAS:CPI-455 is a specific KDM5 inhibitor.Formula:C16H14N4OPurity:97.87% - 99.03%Color and Shape:SolidMolecular weight:278.31Ref: TM-T3552
1mg44.00€2mg55.00€5mg87.00€10mg131.00€25mg284.00€50mg452.00€100mg645.00€500mg1,311.00€1mL*10mM (DMSO)87.00€666-15
CAS:666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer.Cost-effective and quality-assured.Formula:C33H31Cl2N3O5Purity:99.41% - 99.77%Color and Shape:SolidMolecular weight:620.52EED226
CAS:EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.Formula:C17H15N5O3SPurity:98.14% - 99.33%Color and Shape:SolidMolecular weight:369.4MM-589
CAS:MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) protein-protein interaction.Formula:C28H44N8O5Purity:98%Color and Shape:SolidMolecular weight:572.70UNC926
CAS:UNC926 inhibits L3MBTL1 (IC50: 3.9 μM), has affinity for L3MBTL3, blocks 3xMBT-H4K20me1 interactions, doesn't affect 53BP1-H4K20me1 binding.Formula:C16H21BrN2OPurity:97.22%Color and Shape:SolidMolecular weight:337.25Quercetagetin
CAS:Quercetagetin, a flavonoid from Citrus unshiu, inhibits pim-1 kinase (IC50: 0.34 μM), cell-permeable.Formula:C15H10O8Purity:99.65% - 99.76%Color and Shape:SolidMolecular weight:318.24Ref: TM-T8114
1mg88.00€5mg202.00€10mg303.00€25mg510.00€50mg733.00€100mg998.00€500mg1,985.00€1mL*10mM (DMSO)213.00€Niraparib (R-enantiomer)
CAS:Niraparib R-enantiomer (MK 4827 R-enantiomer) is an inhibitor of PARP1(IC50 of 2.4 nM).Formula:C19H20N4OPurity:99.83%Color and Shape:SolidMolecular weight:320.39Ref: TM-T12064
1mg52.00€5mg105.00€10mg177.00€25mg306.00€50mg444.00€100mg620.00€200mg835.00€1mL*10mM (DMSO)116.00€Ilorasertib hydrochloride
CAS:Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:Formula:C25H22ClFN6O2SPurity:98.34%Color and Shape:SolidMolecular weight:525PARP-1-IN-4
CAS:PARP-1-IN-4 is a potent PARP-1 inhibitor with potential see anti-tumor activity, and inhibition of PARP-1 may be used in cancer development.Formula:C22H15Cl2N3O2Purity:99.82%Color and Shape:SolidMolecular weight:424.28Daprodustat
CAS:Daprodustat (GSK1278863) is a HIF-prolyl hydroxylase inhibitor.Formula:C19H27N3O6Purity:97% - 99.82%Color and Shape:SolidMolecular weight:393.43Ref: TM-T3197
1mg39.00€5mg75.00€10mg111.00€25mg177.00€50mg296.00€100mg439.00€200mg645.00€1mL*10mM (DMSO)90.00€DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formula:C26H35N7O5Color and Shape:SolidMolecular weight:525.6PF-06726304 acetate
CAS:PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity.Formula:C24H25Cl2N3O5Purity:98%Color and Shape:SolidMolecular weight:506.38Crebinostat
CAS:Crebinostat: potent HDAC inhibitor, boosts synapsin-1 in neurons, enhances memory and gene Egr1 expression in mice.Formula:C20H23N3O3Purity:95%Color and Shape:SolidMolecular weight:353.41Ref: TM-T27083
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€Povorcitinib phosphate
CAS:Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the treatment of cutaneous lupus erythematosus and Lichen planus.Formula:C23H25F5N7O5PPurity:97.71%Color and Shape:SolidMolecular weight:605.45Ref: TM-T39113L
1mg65.00€2mg95.00€5mg145.00€10mg212.00€25mg359.00€50mg512.00€100mg695.00€200mg937.00€
