GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Products of "GluR"
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3-MATIDA
CAS:3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).Formula:C8H9NO4SPurity:98.41% - 99.05%Color and Shape:SolidMolecular weight:215.23KRP-199 sodium
KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.Formula:C22H12F3N5Na2O7Purity:96.85%Color and Shape:SoildMolecular weight:561.33Ref: TM-T27748L
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€500mg3,734.00€LY3020371 hydrochloride
CAS:LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.Formula:C15H16ClF2NO5SColor and Shape:SolidMolecular weight:395.81JNJ-46778212
CAS:JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.Formula:C20H17FN2O3Purity:99.24%Color and Shape:SolidMolecular weight:352.36A-794282
CAS:A-794282 is a selective antagonist of mGluR1.Formula:C19H18N4OSPurity:≥98%Color and Shape:SolidMolecular weight:350.44GET73
CAS:GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5.Formula:C13H16F3NO2Purity:99.54%Color and Shape:SolidMolecular weight:275.27Ref: TM-T11393
1mg65.00€5mg131.00€10mg202.00€25mg340.00€50mg452.00€100mg638.00€200mg842.00€1mL*10mM (DMSO)177.00€γ-DGG
CAS:gamma-DGG is a competitive blocker of AMPA receptor.Formula:C7H12N2O5Purity:98%Color and Shape:SolidMolecular weight:204.18VU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.Formula:C20H10Cl3N3O3Purity:97.03%Color and Shape:SolidMolecular weight:446.67Ref: TM-T21747
2mg42.00€5mg64.00€10mg97.00€25mg183.00€50mg284.00€100mg425.00€200mg562.00€1mL*10mM (DMSO)78.00€E4CPG
CAS:E4CPG is a novel group I/II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG.Formula:C11H13NO4Purity:99.96%Color and Shape:SolidMolecular weight:223.23L-AP4
CAS:L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).Formula:C4H10NO5PPurity:98%Color and Shape:White To Off-White Crystalline PowderMolecular weight:183.1LY-2300559
CAS:LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.Formula:C26H26O6Purity:100%Color and Shape:SolidMolecular weight:434.48Ref: TM-T27932
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€(S)-MCPG
CAS:(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.Formula:C10H11NO4Purity:98.72%Color and Shape:SolidMolecular weight:209.20VU 0357121
CAS:VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.Formula:C17H17F2NO2Purity:99% - 99.99%Color and Shape:SolidMolecular weight:305.32Fenobam
CAS:Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM).Formula:C11H11ClN4O2Purity:99.93%Color and Shape:SolidMolecular weight:266.68Ref: TM-T15275
1mg35.00€5mg64.00€10mg101.00€25mg170.00€50mg248.00€100mg359.00€200mg497.00€1mL*10mM (DMSO)96.00€DNQX
CAS:DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)Formula:C8H4N4O6Purity:97.15% - 99.10%Color and Shape:Off-White Powder With A Yellow TingeMolecular weight:252.14JNJ-40411813
CAS:JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).Formula:C20H25ClN2OPurity:99.74%Color and Shape:SolidMolecular weight:344.88Ref: TM-TQ0094
1mg55.00€5mg117.00€10mg183.00€25mg306.00€50mg437.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)131.00€S 18986
CAS:S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties inFormula:C10H12N2O2SPurity:99.25%Color and Shape:SolidMolecular weight:224.281H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.Formula:C10H12N2O2SPurity:99.69%Color and Shape:SoildMolecular weight:224.28VU0155041
CAS:VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).Formula:C14H15Cl2NO3Purity:99.52% - 99.56%Color and Shape:SolidMolecular weight:316.18Ref: TM-T3565
2mg40.00€5mg58.00€10mg85.00€25mg145.00€50mg188.00€100mg301.00€200mg435.00€1mL*10mM (DMSO)64.00€(S)-ATPO
CAS:(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.Formula:C11H19N2O7PPurity:98.37% - 99.41%Color and Shape:SolidMolecular weight:322.25
![1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT60224.webp&w=3840&q=75)
