GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Products of "GluR"
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(RS)-3-Hydroxyphenylglycine
CAS:(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.Formula:C8H9NO3Purity:99.92%Color and Shape:SolidMolecular weight:167.16MSOP
CAS:MSOP is a selective antagonist of group III metabotropic glutamate receptor (KD of 51 μM for the L-AP4-sensitive presynaptic mGluR).Formula:C4H10NO6PPurity:98%Color and Shape:SolidMolecular weight:199.1ML337
CAS:ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.Formula:C21H20FNO3Purity:99.09%Color and Shape:SolidMolecular weight:353.39Ref: TM-T23003
1mg35.00€5mg64.00€10mg97.00€25mg207.00€50mg309.00€100mgTo inquire1mL*10mM (DMSO)75.00€(RS)-MCPG
CAS:(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.Formula:C10H11NO4Purity:99.96%Color and Shape:SolidMolecular weight:209.2Ref: TM-T3479
1mg35.00€2mg48.00€5mg70.00€10mg87.00€25mg187.00€50mg338.00€100mg502.00€1mL*10mM (DMSO)74.00€Dipraglurant
CAS:Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.Formula:C16H12FN3Purity:98.7%Color and Shape:SolidMolecular weight:265.29Ref: TM-T15134
1mg97.00€5mg227.00€10mg329.00€25mg723.00€50mg1,064.00€100mg1,415.00€1mL*10mM (DMSO)274.00€VU6004909
CAS:VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.Formula:C21H15FN2O4Purity:96.68% - 98.44%Color and Shape:SolidMolecular weight:378.35Lu AF21934
CAS:Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).Formula:C14H16Cl2N2O2Purity:97.96%Color and Shape:SolidMolecular weight:315.2AMN082
CAS:AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.Formula:C28H30Cl2N2Purity:97.23% - 98.34%Color and Shape:SolidMolecular weight:465.46NBQX Disodium
CAS:NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Formula:C12H6N4Na2O6SPurity:98.22%Color and Shape:SolidMolecular weight:380.24NBQX
CAS:NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.Formula:C12H8N4O6SPurity:97.66% - 99.42%Color and Shape:SolidMolecular weight:336.28Ref: TM-T4113
1mg40.00€5mg89.00€10mg127.00€25mg246.00€50mg369.00€100mg525.00€200mg757.00€1mL*10mM (DMSO)87.00€LY 541850
CAS:LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from humanFormula:C9H13NO4Purity:98%Color and Shape:SolidMolecular weight:199.2GYKI 53655 hydrochloride
CAS:GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.Formula:C19H21ClN4O3Purity:98.02%Color and Shape:SolidMolecular weight:388.85Foliglurax
CAS:Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).Formula:C23H23N3O3SPurity:98%Color and Shape:SolidMolecular weight:421.51MFZ 10-7 hydrochloride
CAS:MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAMFormula:C15H10ClFN2Purity:98%Color and Shape:SolidMolecular weight:272.71cis-PDA
CAS:cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.Formula:C7H11NO4Purity:≥98%Color and Shape:White SolidMolecular weight:173.17Decoglurant
CAS:Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.Formula:C21H11F6N5Purity:99.77%Color and Shape:SolidMolecular weight:447.34Ref: TM-T15090
1mg55.00€5mg117.00€10mg167.00€25mg309.00€50mg434.00€100mg605.00€200mg815.00€1mL*10mM (DMSO)160.00€VU 0364439
CAS:VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).Formula:C18H13Cl2N3O3SPurity:97.90%Color and Shape:SolidMolecular weight:422.29CPPHA
CAS:CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.Formula:C22H15ClN2O4Purity:99.61%Color and Shape:SolidMolecular weight:406.82VU0155041 sodium
CAS:VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.Formula:C14H14Cl2NNaO3Purity:98%Color and Shape:SolidMolecular weight:338.16SIB-1757
CAS:SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)Formula:C12H11N3OPurity:97.37%Color and Shape:SolidMolecular weight:213.24Ref: TM-T8434
2mg39.00€5mg58.00€10mg94.00€25mg170.00€50mg259.00€100mg363.00€200mg509.00€1mL*10mM (DMSO)77.00€
