GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Products of "GluR"
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AZD 9272
CAS:AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.Formula:C14H6F2N4OPurity:97.53%Color and Shape:SolidMolecular weight:284.22CX717
CAS:CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect.Formula:C11H11N3O3Purity:100%Color and Shape:SoildMolecular weight:233.23LY-404187
CAS:LY404187 is a positive allosteric modulator of AMPA receptorsFormula:C19H22N2O2SPurity:99.34%Color and Shape:SolidMolecular weight:342.46Ref: TM-T7706
2mg35.00€5mg52.00€10mg90.00€25mg164.00€50mg239.00€100mg339.00€200mg472.00€1mL*10mM (DMSO)58.00€Cyclothiazide
CAS:Cyclothiazide enhances AMPA receptors, prevents desensitization, and boosts glutamic acid response (EC50 = 3.8µM).Formula:C14H16ClN3O4S2Purity:98.23% - 99.49%Color and Shape:Crystals From Dilute Alcohol SolidMolecular weight:389.88(S)-3-Hydroxyphenylglycine
CAS:(S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).Formula:C8H9NO3Purity:99.18%Color and Shape:SolidMolecular weight:167.16JNJ16259685
CAS:JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19Formula:C20H23NO3Purity:98.31%Color and Shape:SolidMolecular weight:325.4Ref: TM-T5512
1mg48.00€2mg65.00€5mg90.00€10mg140.00€25mg293.00€50mg449.00€100mg655.00€1mL*10mM (DMSO)100.00€MPEP
CAS:MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.Formula:C14H11NPurity:99.54%Color and Shape:SolidMolecular weight:193.24LSN2463359
CAS:LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.Formula:C16H15N3OPurity:99.36%Color and Shape:SolidMolecular weight:265.31Ref: TM-T27854
2mg35.00€5mg52.00€10mg85.00€25mg170.00€50mg259.00€100mg383.00€200mg545.00€1mL*10mM (DMSO)58.00€VU0650786
CAS:VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.Formula:C18H15ClFN5O2Purity:99.09%Color and Shape:SolidMolecular weight:387.8Ref: TM-T13318
1mg96.00€5mg235.00€10mg329.00€25mg560.00€50mg800.00€100mg1,103.00€1mL*10mM (DMSO)259.00€FITM
CAS:FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).Formula:C18H18FN5OSPurity:97.25%Color and Shape:SolidMolecular weight:371.43Ref: TM-T7292
1mg35.00€2mg47.00€5mg70.00€10mg97.00€25mg187.00€50mg283.00€100mg416.00€1mL*10mM (DMSO)65.00€VU0364770
CAS:VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGluFormula:C12H9ClN2OPurity:99.65% - 99.92%Color and Shape:SolidMolecular weight:232.67EGLU
CAS:EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.Formula:C7H13NO4Purity:99.98%Color and Shape:SolidMolecular weight:175.18DCB
CAS:DCB is an mGluR5 allosteric ligand that blocks mGluR modulation, countering DMeOB and DFB effects.Formula:C14H10Cl2N2Purity:99.12% - 99.9%Color and Shape:SolidMolecular weight:277.15Ref: TM-T22711
5mg39.00€10mg50.00€25mg105.00€50mg170.00€100mg273.00€200mg378.00€1mL*10mM (DMSO)42.00€(E/Z)-SIB-1893
CAS:(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.Formula:C14H13NPurity:99.92%Color and Shape:SolidMolecular weight:195.26Org-26576
CAS:Org-26576 is a positive allosteric modulator of the AMPA receptor.Formula:C11H12N2O2Purity:99.67%Color and Shape:SolidMolecular weight:204.23Ref: TM-T16402
5mg47.00€10mg70.00€25mg104.00€50mg150.00€100mg256.00€200mg379.00€1mL*10mM (DMSO)50.00€Biphenylindanone A
CAS:Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.Formula:C30H30O4Purity:98%Color and Shape:SolidMolecular weight:454.56Piracetam
CAS:Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.Formula:C6H10N2O2Purity:97.16%Color and Shape:Crystals From Isopropanol SolidMolecular weight:142.16MTEP hydrochloride
CAS:MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)Formula:C11H9ClN2SPurity:99.58%Color and Shape:SolidMolecular weight:236.72AMN082 free base
CAS:AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.Formula:C28H28N2Purity:97.75% - 97.79%Color and Shape:SolidMolecular weight:392.54Ref: TM-T21935L
1mg39.00€5mg78.00€10mg111.00€25mg216.00€50mg354.00€100mg567.00€200mg793.00€1mL*10mM (DMSO)89.00€VU-1545
CAS:VU-1545 is mGlu5 positive allosteric modulator.Formula:C22H15FN4O3Purity:98.80%Color and Shape:SolidMolecular weight:402.38
