GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Products of "GluR"
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Licostinel
CAS:Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.Formula:C8H3Cl2N3O4Purity:98.02%Color and Shape:SolidMolecular weight:276.031-BCP
CAS:1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.Formula:C13H15NO3Purity:99.60%Color and Shape:SolidMolecular weight:233.26Chelidamic acid
CAS:Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.Formula:C7H5NO5Purity:98.11%Color and Shape:Pale Yellow PowderMolecular weight:183.12DL-AP3
CAS:DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.Formula:C3H8NO5PPurity:98.18% - ≥98%Color and Shape:White PowderMolecular weight:169.07VU6012962
CAS:VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).Formula:C21H19F3N4O4Purity:97% - 98.31%Color and Shape:SolidMolecular weight:448.4Ref: TM-T13323
1mg37.00€2mg52.00€5mg79.00€10mg126.00€25mg236.00€50mg425.00€100mg625.00€1mL*10mM (DMSO)87.00€GYKI 52466 dihydrochloride
CAS:GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.Formula:C17H17Cl2N3O2Purity:99.38%Color and Shape:SolidMolecular weight:366.24Pomaglumetad methionil anhydrous
CAS:LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.Formula:C12H18N2O7S2Purity:98%Color and Shape:SolidMolecular weight:366.41CX516
CAS:CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.Formula:C14H15N3OPurity:99.29% - ≥95%Color and Shape:Tan SolidMolecular weight:241.29Transtorine
CAS:Transtorine (1,4-DIHYDRO-4-OXOQUINOLINE-2-CARBOXYLIC ACID) is a GluR and NMDA inhibitor.Formula:C10H7NO3Purity:99.36%Color and Shape:SolidMolecular weight:189.17HBT1
CAS:HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neuronsFormula:C16H17F3N4O2SPurity:99.52%Color and Shape:SolidMolecular weight:386.39MNI 137
CAS:MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.Formula:C15H9BrN4OPurity:97.21%Color and Shape:SolidMolecular weight:341.16trans-ACPD
CAS:trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.Formula:C7H11NO4Purity:99.53%Color and Shape:SolidMolecular weight:173.17Ref: TM-T3484
1mg48.00€2mg63.00€5mg89.00€10mg147.00€25mg279.00€50mg505.00€100mg730.00€1mL*10mM (DMSO)74.00€CFMTI
CAS:CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.Formula:C19H16FN5OPurity:97.23%Color and Shape:SolidMolecular weight:349.36Ref: TM-T3482
1mg60.00€2mg87.00€5mg127.00€10mg180.00€25mg321.00€50mg455.00€100mg635.00€1mL*10mM (DMSO)140.00€(R)-3,4-DCPG HCl
(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatalFormula:C10H10ClNO6Purity:98.36% - 99.89%Color and Shape:SoildMolecular weight:275.64(R)-ADX-47273
CAS:(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).Formula:C20H17F2N3O2Purity:99.87%Color and Shape:SolidMolecular weight:369.36Ref: TM-T13441
2mg42.00€5mg65.00€10mg94.00€25mg170.00€50mg259.00€100mg391.00€200mg545.00€1mL*10mM (DMSO)71.00€AMPA receptor modulator-2
CAS:AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.Formula:C15H6F6N4OSPurity:99.62%Color and Shape:SolidMolecular weight:404.29Ref: TM-T37734
1mg123.00€5mg298.00€10mg393.00€25mg628.00€50mg905.00€100mg1,254.00€1mL*10mM (DMSO)328.00€VU0155094
CAS:VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.Formula:C24H24N2O4SPurity:98.00%Color and Shape:SolidMolecular weight:436.52Ref: TM-T9011
1mg65.00€5mg116.00€10mg170.00€25mg284.00€50mg393.00€100mg567.00€200mg748.00€1mL*10mM (DMSO)134.00€MFZ 10-7
CAS:MFZ 10-7 is anegative allosteric modulator of the mGluR5.Formula:C15H9FN2Purity:98.82%Color and Shape:SolidMolecular weight:236.24Farampator
CAS:Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.Formula:C12H13N3O2Purity:99.76% - 99.83%Color and Shape:SolidMolecular weight:231.25Ref: TM-T3957
2mg34.00€5mg52.00€10mg74.00€25mg140.00€50mg235.00€100mg350.00€200mg497.00€1mL*10mM (DMSO)58.00€JNJ-42153605
CAS:JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).Formula:C22H23F3N4Purity:97.25% - 98.57%Color and Shape:SolidMolecular weight:400.44Ref: TM-T3451
1mg34.00€2mg52.00€5mg81.00€10mg105.00€25mg180.00€50mg279.00€100mg396.00€200mg555.00€1mL*10mM (DMSO)84.00€
