AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Products of "AChR"
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Terodiline hydrochloride
CAS:Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),Formula:C20H28ClNPurity:98%Color and Shape:SolidMolecular weight:317.9Nitenpyram
CAS:Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.Formula:C11H15ClN4O2Purity:98.42%Color and Shape:Light-Yellow CrystalMolecular weight:270.72nAChR agonist 1
CAS:nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.Formula:C20H18ClNO3S2Purity:97.59%Color and Shape:SolidMolecular weight:419.94Ref: TM-T12165
1mg94.00€5mg170.00€10mg259.00€25mg424.00€50mg562.00€100mg775.00€200mg1,026.00€1mL*10mM (DMSO)192.00€Pancuronium dibromide
CAS:Pancuronium dibromide (Pavulon), a competitive AChR antagonist, acts as a skeletal muscle relaxant. Pancuronium dibromide blocks neuromuscular transmission.Formula:C35H60Br2N2O4Purity:99.86%Color and Shape:solidMolecular weight:732.67Ref: TM-T0166
5mg38.00€10mg55.00€25mg82.00€50mg115.00€100mg188.00€200mg235.00€500mg394.00€1mL*10mM (DMSO)63.00€Darifenacin hydrobromide
CAS:Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.Formula:C28H31BrN2O2Purity:100% - 99.75%Color and Shape:SolidMolecular weight:505.45VU 0255035
CAS:VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.Formula:C18H20N6O3S2Purity:96.53% - 98.26%Color and Shape:SolidMolecular weight:432.52Adiphenine hydrochloride
CAS:Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.Formula:C20H25NO2·HClPurity:97.76% - 99.13%Color and Shape:White Or Almost White PowderMolecular weight:347.88Methacholine Chloride
CAS:Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of acetylcholine.Formula:C8H18ClNO2Purity:99.37% - 99.74%Color and Shape:White Hygroscopic Crystals With Slight Odor Of Dead FishMolecular weight:195.69Ispronicline
CAS:Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitiveFormula:C14H22N2OPurity:96.49% - 99.16%Color and Shape:SolidMolecular weight:234.348-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Formula:C5H6N6Purity:98.34%Color and Shape:SolidMolecular weight:150.14PNU-120596
CAS:PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.Formula:C13H14ClN3O4Purity:98.34%Color and Shape:SolidMolecular weight:311.72suvn-911
CAS:suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.Formula:C11H14Cl2N2OPurity:98.88%Color and Shape:SolidMolecular weight:261.15Ref: TM-T9787
1mg71.00€5mg140.00€10mg215.00€25mg359.00€50mg510.00€100mg695.00€200mg937.00€1mL*10mM (DMSO)182.00€MHP 133
CAS:MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).Formula:C17H20ClN5O3Purity:98%Color and Shape:SolidMolecular weight:377.83Ipratropium Bromide
CAS:Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.Formula:C20H30BrNO3Purity:99.91%Color and Shape:SolidMolecular weight:412.37Varenicline Tartrate
CAS:Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist.Formula:C13H13N3·C4H6O6Purity:98.23% - 98.32%Color and Shape:Tan SolidMolecular weight:361.35GSK233705
CAS:GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.Formula:C24H29BrN2Purity:99.67% - 99.76%Color and Shape:SolidMolecular weight:425.4DMAB-anabaseine dihydrochloride
CAS:DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containingFormula:C19H23Cl2N3Purity:99.86%Color and Shape:SolidMolecular weight:364.31A-867744
CAS:A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).Formula:C20H19ClN2O3SPurity:95.66%Color and Shape:SolidMolecular weight:402.89MK-7622
CAS:MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.Formula:C25H25N3O2Purity:99.77% - 99.8%Color and Shape:SolidMolecular weight:399.48JHU37152
CAS:JHU37152 is a DREADD agonist; Ki: 1.8 nM at hM3Dq, 8.7 nM at hM4Di; EC50: 5 nM (hM3Dq), 0.5 nM (hM4Di) in HEK-293 cell assays.Formula:C19H20ClFN4Purity:99.72%Color and Shape:SolidMolecular weight:358.84Ref: TM-T9019
2mg35.00€5mg52.00€10mg90.00€25mg170.00€50mg255.00€100mg375.00€200mg533.00€1mL*10mM (DMSO)58.00€
