AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Products of "AChR"
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Clothianidin
CAS:Clothianidin (TI 435), an insecticide, stimulates nAChR as acetylcholine agonist, not AChE inhibitor.Formula:C6H8ClN5O2SPurity:99.71%Color and Shape:Solid PowderMolecular weight:249.68Tropicamide
CAS:Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.Formula:C17H20N2O2Purity:99.78% - 99.94%Color and Shape:White PowderMolecular weight:284.35Glycopyrrolate
CAS:Glycopyrrolate: muscarinic antagonist, antispasmodic for GI issues, reduces salivation with anesthesia.Formula:C19H28BrNO3Purity:99.41% - 99.64%Color and Shape:SolidMolecular weight:398.33PNU-282987 S enantiomer free base
CAS:PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).Formula:C14H17ClN2OPurity:99.74%Color and Shape:SolidMolecular weight:264.75Ref: TM-T7695
1mg97.00€5mg235.00€10mg329.00€25mg509.00€50mg695.00€100mg940.00€200mg1,264.00€1mL*10mM (DMSO)273.00€JNJ-39393406
CAS:JNJ-39393406 is an α7 nicotinic acetylcholine receptor positive allosteric modulator for the study of tobacco dependence and Alzheimer's disease.Formula:C19H18F2N6O3Purity:98.36%Color and Shape:SolidMolecular weight:416.38VU0238441
CAS:VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.Formula:C16H9ClF3NO2Purity:100%Color and Shape:SolidMolecular weight:339.7(±)-Darifenacin
CAS:(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.Formula:C28H30N2O2Color and Shape:SolidMolecular weight:426.55Pozanicline dihydrochloride
CAS:Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki = 16.7 nM)Formula:C11H18Cl2N2OPurity:98%Color and Shape:SolidMolecular weight:265.18Cyclodrine hydrochloride
CAS:Cyclodrine hydrochloride is a dual cholinergic muscarinic receptor (mAChR) and nicotinic receptor (nAChR) antagonist that can be used in the study ofFormula:C19H30ClNO3Purity:98.59%Color and Shape:SolidMolecular weight:355.9Tiotropium Bromide hydrate
CAS:Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.Formula:C19H24BrNO5S2Purity:98.44% - 99.41%Color and Shape:SolidMolecular weight:490.43TQS
CAS:TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.Formula:C22H20N2O2SPurity:98.56%Color and Shape:SolidMolecular weight:376.47Ref: TM-T23469
2mg34.00€5mg50.00€10mg80.00€25mg156.00€50mg243.00€100mg359.00€200mg510.00€1mL*10mM (DMSO)52.00€Pipecuronium bromide
CAS:Pipecuronium bromide (RGH-1106) is an nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker that causes muscle relaxation.Formula:C35H62Br2N4O4Purity:100%Color and Shape:PowderMolecular weight:762.7TC-2216
CAS:TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.Formula:C12H17N3Purity:100.00%Color and Shape:SolidMolecular weight:203.28Sulfoxaflor
CAS:Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide. Cost-effective and quality-assured.Formula:C10H10F3N3OSPurity:99.87%Color and Shape:SolidMolecular weight:277.27Metixene hydrochloride
CAS:Metixene hydrochloride is an anticholinergic antiparkinsonian agent.Formula:C20H24ClNSPurity:98%Color and Shape:SolidMolecular weight:345.93Methscopolamine
CAS:Methscopolamine (Hyoscine methyl bromide) (Pamine), as a natural plant alkaloid, is a muscarinic acetylcholine receptor blocker.Formula:C18H24BrNO4Purity:99.12% - ≥98%Color and Shape:SolidMolecular weight:398.29Metixene hydrochloride hydrate
CAS:Metixene HCl hydrate is a potential anticholinergic for Parkinson's with IC50 of 55 nM and Ki of 15 nM against muscarine receptors.Formula:C20H26ClNOSPurity:99.88%Color and Shape:SolidMolecular weight:363.95JHU37160
CAS:JHU37160 is a DREADD agonist with Ki of 1.9 nM for hM3Dq, 3.6 nM for hM4Di, and EC50 of 18.5 nM (hM3Dq), 0.2 nM (hM4Di) in HEK-293 cell assays.Formula:C19H20ClFN4Purity:99.87%Color and Shape:SolidMolecular weight:358.84Vesamicol hydrochloride
CAS:Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.Formula:C17H26ClNOPurity:98.31%Color and Shape:SolidMolecular weight:295.85Cyclopentolate Hydrochloride
CAS:Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.Formula:C17H26ClNO3Purity:99.91%Color and Shape:SolidMolecular weight:327.85
