AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Products of "AChR"
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Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurity:99.84%Color and Shape:SolidMolecular weight:390.4Ref: TM-T9694
1mg127.00€5mg305.00€10mg550.00€25mg882.00€50mg1,206.00€100mg1,605.00€1mL*10mM (DMSO)338.00€Coluracetam
CAS:Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.Formula:C19H23N3O3Purity:99.96%Color and Shape:SolidMolecular weight:341.4A 582941 HCl (848591-90-2(free base))
A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing propertiesFormula:C17H21ClN4Purity:99.83%Color and Shape:SolidMolecular weight:316.83Ref: TM-T8725
1mg88.00€5mg172.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)170.00€Orphenadrine Citrate
CAS:Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.Formula:C18H23NO·C6H8O7Purity:98% - 99.51%Color and Shape:White SolidMolecular weight:461.54BP-TQS
CAS:4BP-TQS is an allosteric agonist of α7 nAChRs.Formula:C18H17BrN2O2SPurity:99.96%Color and Shape:SolidMolecular weight:405.31α-Muricholic acid
CAS:α-Muricholic acid is the most abundant primary bile acid in rodents.Formula:C24H40O5Purity:98%Color and Shape:SolidMolecular weight:408.57Succinylcholine Chloride Dihydrate
CAS:Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.Formula:C14H30N2O4·2Cl·2H2OPurity:99.87%Color and Shape:White SolidMolecular weight:397.34Propantheline bromide
CAS:Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscleFormula:C23H30BrNO3Purity:95% - ≥98%Molecular weight:448.4ML380
CAS:ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).Formula:C23H25F3N4O3SPurity:99.69%Color and Shape:SolidMolecular weight:494.53Ref: TM-T28069
2mg49.00€5mg74.00€10mg119.00€25mg188.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)82.00€(-)-(S)-B-973B
CAS:(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.Formula:C24H26F2N6OPurity:99.52%Color and Shape:SolidMolecular weight:452.5GP531
CAS:GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.Formula:C16H21N5O4Color and Shape:SolidMolecular weight:347.37Cevimeline hydrochloride hemihydrate
CAS:Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.Formula:C20H38Cl2N2O3S2Purity:98%Color and Shape:SolidMolecular weight:489.55Nebracetam hydrochloride
CAS:Nebracetam HCl (WEB 1881 FU) is an M1-muscarinic agonist nootropic, increasing intracellular Ca2+ with an EC50 of 1.59 mM.Formula:C12H17ClN2OPurity:99.23%Color and Shape:SolidMolecular weight:240.729Ref: TM-T12201
5mg48.00€10mg71.00€25mg108.00€50mg160.00€100mg226.00€200mg331.00€1mL*10mM (DMSO)50.00€VU 0365114
CAS:VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).Formula:C22H14F3NO3Purity:97.29%Color and Shape:SolidMolecular weight:397.35Ref: TM-T13325
2mg38.00€5mg58.00€10mg82.00€25mg137.00€50mg224.00€100mg335.00€200mg469.00€1mL*10mM (DMSO)65.00€Tazomeline
CAS:Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity.Formula:C14H23N3S2Purity:100%Color and Shape:SolidMolecular weight:297.48Oxyphencyclimine Hydrochloride
CAS:Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.Formula:C20H29ClN2O3Purity:99.55%Color and Shape:SolidMolecular weight:380.91SIB 1553A
CAS:SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.Formula:C13H19NOSPurity:99.64%Color and Shape:SoildMolecular weight:237.36Ref: TM-T16881L
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€1mL*10mM (DMSO)47.00€Diphenmanil methylsulfate
CAS:Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors.Formula:C20H24N·CH3O4SPurity:98% - 99.27%Color and Shape:SolidMolecular weight:389.51Iperoxo
CAS:Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.Formula:C10H17IN2O2Purity:98.93%Color and Shape:SolidMolecular weight:324.16Ref: TM-T25538
1mg50.00€5mg107.00€10mg187.00€25mg411.00€50mg613.00€100mg873.00€500mg1,768.00€1mL*10mM (DMSO)117.00€Soclenicant
CAS:Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availabilityFormula:C24H26N4O3Purity:99.57%Color and Shape:SoildMolecular weight:418.49Ref: TM-T203814
1mg201.00€5mg497.00€10mg701.00€25mg1,094.00€50mg1,508.00€100mg1,931.00€200mg2,637.00€
