TNF
Los inhibidores del factor de necrosis tumoral (TNF) son compuestos que bloquean la actividad del TNF, una citocina involucrada en la inflamación y la regulación de la apoptosis. El TNF puede inducir apoptosis en algunos tipos celulares mientras promueve la supervivencia y la inflamación en otros. Inhibir el TNF es crucial en el tratamiento de enfermedades autoinmunes, condiciones inflamatorias crónicas y ciertos tipos de cáncer. Los inhibidores de TNF ayudan a modular la respuesta inmunitaria y a reducir el daño tisular causado por la inflamación excesiva. En CymitQuimica, ofrecemos una amplia gama de inhibidores de TNF de alta calidad para apoyar su investigación en inmunología, inflamación y apoptosis.
Productos de "TNF"
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Belantamab
CAS:Belantamab (GSK2857914) is a humanized IgG1 monoclonal antibody targeting BCMA, used for creating conjugates like mafodotin.Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Forma y color:LiquidPeso molecular:146.06 kDa(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Fórmula:C27H39N5O7Pureza:98.30% - 99.15%Forma y color:SolidPeso molecular:545.63TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.Fisetin
CAS:Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.Fórmula:C15H10O6Pureza:94.14% - 98.31%Forma y color:Yellow To Brown Crystalline PowderPeso molecular:286.24C25-140
CAS:C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.Fórmula:C26H31N7OPureza:98.81%Forma y color:SolidPeso molecular:457.57Hederacoside D
CAS:Hederacoside D is a bioactive saponins from Hedera helix.Fórmula:C53H86O22Pureza:94.94% - 99.30%Forma y color:SolidPeso molecular:1075.24SPD304 dihydrochloride
CAS:SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.Fórmula:C32H34Cl2F3N3O2Pureza:99.25%Forma y color:SolidPeso molecular:620.53Etanercept
CAS:Etanercept is a fusion protein consisting of the soluble portion of the p75-tumor necrosis factor receptor (TNFR) and the Fc fragment of human IgG1 and is commonly used to treat patients with rheumatoid arthritis.Cost-effective and quality-assured.Pureza:98%Forma y color:LiquidAtibuclimab
CAS:Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.Pureza:> 95% - > 95%Forma y color:LiquidPeso molecular:145.28 kDaEupatolide
CAS:Eupatolide, from Inula japonica flowers, has anti-inflammatory properties and aids in researching TRAIL resistance in breast cancer.Fórmula:C15H20O3Pureza:98%Forma y color:SolidPeso molecular:248.32Alethine
CAS:Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.Fórmula:C10H22N4O2S2Pureza:98.82%Forma y color:SolidPeso molecular:294.44RIPK-IN-4
CAS:RIPK-IN-4 is an effective and selective inhibitor of RIPK2. It also has excellent oral bioavailability (IC50: 3 nM).Fórmula:C18H21FN4O3SPureza:98%Forma y color:SolidPeso molecular:392.45Forsythoside B
CAS:Forsythoside B inhibits LPS, NF-κB, inflammation, offers neuroprotection, reduces ischemia injury, and has antioxidant and antisepsis effects.Fórmula:C34H44O19Pureza:98% - 98.78%Forma y color:SolidPeso molecular:756.7(R)-STU104
CAS:(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.Fórmula:C18H18O4Pureza:98.91% - 99.42%Forma y color:SolidPeso molecular:298.33Tebentafusp
CAS:Tebentafusp (IMCgp100) is a protein that targets gp100 with potential anti-tumor activity.Forma y color:LiquidEJMC-1
CAS:EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.Fórmula:C17H11ClN2O4SPureza:97.69%Forma y color:SolidPeso molecular:374.8Ref: TM-T60054
1mg144,00€2mg208,00€5mg351,00€10mg500,00€25mg730,00€50mg998,00€100mg1.349,00€500mg2.707,00€4-methoxylonchocarpin
CAS:4-methoxylonchocarpin, from Abrus precatorius roots, inhibits NF-κB, LPS/TLR4 in macrophages, and mouse colitis.Fórmula:C21H20O4Pureza:98%Forma y color:SoildPeso molecular:336.38Ref: TM-T6S1597
1mg49,00€5mg90,00€10mg144,00€25mg254,00€50mg424,00€100mg613,00€1mL*10mM (DMSO)114,00€QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Fórmula:C22H20N4OPureza:98.16% - 99.17%Forma y color:White SolidPeso molecular:356.42Ref: TM-T6204
1mg43,00€2mg57,00€5mg93,00€10mg140,00€25mg226,00€50mg329,00€100mg490,00€1mL*10mM (DMSO)93,00€Certolizumab pegol
CAS:Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.Forma y color:Liquid
