TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Products of "TNF"
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Belantamab
CAS:Belantamab (GSK2857914) is a humanized IgG1 monoclonal antibody targeting BCMA, used for creating conjugates like mafodotin.Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:146.06 kDa(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Formula:C27H39N5O7Purity:98.30% - 99.15%Color and Shape:SolidMolecular weight:545.63TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.Fisetin
CAS:Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.Formula:C15H10O6Purity:94.14% - 98.31%Color and Shape:Yellow To Brown Crystalline PowderMolecular weight:286.24C25-140
CAS:C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.Formula:C26H31N7OPurity:98.81%Color and Shape:SolidMolecular weight:457.57Hederacoside D
CAS:Hederacoside D is a bioactive saponins from Hedera helix.Formula:C53H86O22Purity:94.94% - 99.30%Color and Shape:SolidMolecular weight:1075.24SPD304 dihydrochloride
CAS:SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.Formula:C32H34Cl2F3N3O2Purity:99.25%Color and Shape:SolidMolecular weight:620.53Etanercept
CAS:Etanercept is a fusion protein consisting of the soluble portion of the p75-tumor necrosis factor receptor (TNFR) and the Fc fragment of human IgG1 and is commonly used to treat patients with rheumatoid arthritis.Cost-effective and quality-assured.Purity:98%Color and Shape:LiquidAtibuclimab
CAS:Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145.28 kDaEupatolide
CAS:Eupatolide, from Inula japonica flowers, has anti-inflammatory properties and aids in researching TRAIL resistance in breast cancer.Formula:C15H20O3Purity:98%Color and Shape:SolidMolecular weight:248.32Alethine
CAS:Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.Formula:C10H22N4O2S2Purity:98.82%Color and Shape:SolidMolecular weight:294.44RIPK-IN-4
CAS:RIPK-IN-4 is an effective and selective inhibitor of RIPK2. It also has excellent oral bioavailability (IC50: 3 nM).Formula:C18H21FN4O3SPurity:98%Color and Shape:SolidMolecular weight:392.45Forsythoside B
CAS:Forsythoside B inhibits LPS, NF-κB, inflammation, offers neuroprotection, reduces ischemia injury, and has antioxidant and antisepsis effects.Formula:C34H44O19Purity:98% - 98.78%Color and Shape:SolidMolecular weight:756.7(R)-STU104
CAS:(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.Formula:C18H18O4Purity:98.91% - 99.42%Color and Shape:SolidMolecular weight:298.33Tebentafusp
CAS:Tebentafusp (IMCgp100) is a protein that targets gp100 with potential anti-tumor activity.Color and Shape:LiquidEJMC-1
CAS:EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.Formula:C17H11ClN2O4SPurity:97.69%Color and Shape:SolidMolecular weight:374.8Ref: TM-T60054
1mg144.00€2mg208.00€5mg351.00€10mg500.00€25mg730.00€50mg998.00€100mg1,349.00€500mg2,707.00€4-methoxylonchocarpin
CAS:4-methoxylonchocarpin, from Abrus precatorius roots, inhibits NF-κB, LPS/TLR4 in macrophages, and mouse colitis.Formula:C21H20O4Purity:98%Color and Shape:SoildMolecular weight:336.38Mulberroside A
CAS:1.Formula:C26H32O14Purity:99.05% - 99.4%Color and Shape:SolidMolecular weight:568.52Ref: TM-T6S1597
1mg49.00€5mg90.00€10mg144.00€25mg254.00€50mg424.00€100mg613.00€1mL*10mM (DMSO)114.00€QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Formula:C22H20N4OPurity:98.16% - 99.17%Color and Shape:White SolidMolecular weight:356.42Ref: TM-T6204
1mg43.00€2mg57.00€5mg93.00€10mg140.00€25mg226.00€50mg329.00€100mg490.00€1mL*10mM (DMSO)93.00€Certolizumab pegol
CAS:Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.Color and Shape:Liquid
